Wisdom Panel™ Complete for Cats – In-Depth Review

The Wisdom Panel™ Complete for Cats is one of the most comprehensive feline DNA test kits available to the public. It promises insights into breed composition, genetic traits, health predispositions, blood type, and more—all from a simple cheek swab. For cat lovers who want to better understand their feline companion’s background or preempt potential health concerns, this kit offers a wealth of actionable information.

We put this product to the test using Abby, a 17-year-old female cat. The kit was submitted in July 2025, and the results delivered an impressively detailed 12-page report.

What You Get With the Wisdom Panel Complete

• Screens over 70 cat breeds and populations
• Genetic health screening for 45+ conditions
• Blood type and transfusion risk
• Traits like coat color, type, tail length, and more
• Multi-generational family tree

The kit comes with 2 brush swabs that you need to stick in your cat’s mouth, swirl/rub along their gums for 15 seconds each. Place the swabs back in the packaging, seal the pre-stamped box and send back. You’ll want to create an account and enter the kit’s number to activate it. After waiting a couple of weeks, we got her full report back. Let’s dive into Abby’s actual results to see how the promises stack up.

Genetic Makeup: Breed Breakdown

Abby’s report revealed a fascinating mix of feline ancestry:

• 53% American Domestic Cat
• 14% European Domestic Cat
• 12% Highlander
• 12% Maine Coon
• 8% Norwegian Forest Cat
• 1% Sphynx

The family tree visualization in the report shows multiple generations of mixed domestic lineage with some strong Maine Coon and Highlander influence. I always assumed she had some Maine Coon genes, but I wasn’t expecting the Highlander or the Sphynx. This test demonstrates the power of deep ancestry analysis—something you’d never guess just by appearance.

Standout Feature: Unlike basic breed ID kits, Wisdom Panel provides a multi-generation family tree that’s helpful for understanding how ancestry blends over time.

Genetic Diversity & Heterozygosity

Abby’s heterozygosity was 41%, which places her at the upper end of the typical range for random-bred cats (29%–41%). This suggests a well-diversified genome—generally a good sign for robust health and vitality.

Why It Matters: Genetic diversity helps protect against inherited diseases and can indicate how “inbred” or “hybrid” a cat may be. Abby’s results suggest a healthy blend.

Blood Type & Transfusion Risk

Wisdom Panel identifies blood type A, the most common in cats. However, Abby has a moderate transfusion risk, meaning it’s important to blood-type match her carefully if a transfusion is ever needed.

This test checks for multiple variants of the CMAH gene, responsible for blood typing. Abby tested negative for all B and AB variants—confirming a strong confidence in the Type A result.

Genetic Health Screening: 49 Conditions Tested

One of the most valuable aspects of the Complete kit is its comprehensive genetic health screen.

Abby’s Results:

• At Risk Conditions: 0
• Carrier Conditions: 1
• Clear Conditions: 48

The one condition Abby is a carrier for is:

• Pyruvate Kinase Deficiency (PK)
  A condition that can lead to anemia if two mutated genes are inherited. Abby only has one copy, so she won’t develop the condition but could pass it on if bred.

Peace of Mind: Knowing she’s clear of high-risk conditions like Hypertrophic Cardiomyopathy (especially notable with her Maine Coon heritage) is huge for her long-term wellness planning.

Physical Traits: What Her DNA Says About Her Appearance

Wisdom Panel decoded multiple traits:

Coat & Color

• Long Hair (FGF5): Abby has two long-hair gene variants—confirming her fluffy coat.
• Colorpoints Possible (TYR gene): She carries one Siamese-style colorpoint variant, meaning subtle cooler shades may appear, especially on ears or paws.
• White Spotting (KIT gene): One copy present, indicating a partly or fully white coat—perfect match for cats with chest or paw markings.

Extra Features

• No polydactyl (extra toes) variants
• No bobtail or short-tail genes
• No hairlessness or rexing genes

Wisdom Panel was able to identify dozens of potential coat and body traits, even if they don’t visibly express. This can help decode subtle physical quirks or explain unexpected features in a litter of kittens.

User Experience & Report Design

PDF Report Features:

• Well-organized and visually rich
• Includes clear breed diagrams and health glossaries
• Actionable, with veterinary insights and next steps for any flagged conditions

The breed visuals and trait results are especially digestible for non-geneticists, and each health risk includes a concise “What it means” and “What to do” section.

Final Thoughts: Is It Worth It?

For Abby, the Wisdom Panel Complete Test:

• Confirmed her surprising mixed ancestry
• Revealed her to be a long-haired, genetically diverse cat with no major health risks
• Flagged a single carrier status (PKDef) that wouldn’t otherwise be obvious
• Provided blood type insights crucial for emergency care

Wisdom Panel™ Complete for Cats delivers on its promise of in-depth feline insights. Whether you’re curious about your cat’s heritage, want to check for hidden health risks, or are simply a data-loving pet parent, this test offers real value—especially when paired with veterinary care.

Abby’s results demonstrate how useful this test can be for peace of mind and deeper understanding of a beloved pet’s genetics.

Buy Now: $103.99 (Current Sale Price). Regularly: $129.99.